Cy-Ubpy
- for Organic Synthesis
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at RT.
- CAS RN® :
- 1802339-58-7
- Molecular Formula :
- C23H24N4O
- Molecular Weight :
- 372.46
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- Structural Formula
- Label
- Packing
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1G
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250mg
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Document
Overview
The C-H (carbon-hydrogen) activation reaction has been attracting much attention in organic synthesis reactions since inert C-H bonds have been cleaved and simultaneously creates new bonds. Though this reaction contribute to reduce and simplify multi-step reactions, it is necessary to be recognized only specific reaction point from a lot of C-H bonds in compounds, so that selectivity of C-H bond is significantly important. Directed by an interaction between Cy-Ubpy* and carbonyl groups of aromatic substrates will lead to a meta-selective C-H borylation [B(pin)]. In addition, it is possible to synthesize the diverse urea ligands different from Cy-Ubpy by using the precursor Amino-bpy and changing various isocyanate compounds.
*Cy-Ubpy = Cyclohexyl-Urea bipyridine
Features
- Excellent ligand for C-H borylated in both yield and regioselectivity
- Reaction examples (Reaction mechanisms)
- A meta-selective C-H borylation of aromatic compounds by controlling the position of the catalytically active iridium center using hydrogen bonding between a urea moiety of a ligand and functional groups of the substrate
Applications
Reaction Mechanism
Meta-selective C-H borylation
Overview / Applications
| Outline | This product is for research use only. Do not administer it to human.This product is a ligand for coupling reaction developed by Prof. Kanai and Prof. Kuninobu. It is possible to convert carbon - hydrogen bond (C - H) to carbon - boron bond (C - B) meta selectively against amide of aromatic ring. Reference:Kuninobu, Y., Nagase, M. and Kanai, M.: Nat. Chem., 7, 712 (2015). |
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Property
Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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