Camptothecin
- for Biochemistry
- Specification Assay :
- 98.0+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at 2-10 degrees C.
- CAS RN® :
- 7689-03-4
- Molecular Formula :
- C20H16N2O4
- Molecular Weight :
- 348.35
-
Close -
Close
Close -
Close
Close
- Structural Formula
- Label
- Packing
- SDS
|
Comparison
|
Product Number
|
Package Size
|
Price
|
Inventory
|
|
|---|---|---|---|---|---|
|
|
|
100mg
|
|
In stock in Japan |
|
|
|
|
500mg
|
|
In stock in Japan |
Document
Application
Overview / Applications
| Outline | An alkaloid contained in Nothapodytes foetida and Camptotheca acuminata. It has a quinoline skeleton but, biosynthetically, it is a resembling compound of indole alkaloid.This product is a reversible inhibitor of DNA topoisomerase I and it binds to topoisomerase-DNA complex leading to stabilization. It exhibits antileukemic and antitumor activities and inhibits activation of HIV-1 by Tat. It exhibits cytotoxicity to tumorigenetic cells but not to non-tumorigenetic cells. It also induces apoptosis in HL-60 cells and mouse thymus cells.Anticancer irinotecan (Topotecin) is one of its derivatives. |
|---|
Property
| Appearance | Slightly yellow - brown, crystalline powder - powder |
|---|---|
| Origin / Source | Mappia sp. |
| Specific Rotation | +38 - +48 degrees (D/20 degrees C)(c=0.4,CHCl3-CH3OH) |
Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
Product content may differ from the actual image due to minor specification changes etc.
If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.