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Anti ATRX, Monoclonal Antibody (AMab-6)

for Immunochemistry
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
Source :
Human
Host :
Mouse
Clone No. :
AMab-6
Classification :
Monoclonal
  • Structural Formula
  • Label
  • Packing
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Product Number
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Distributor
017-26751
Barcode No
4548995057563
100ug
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In stock in Japan

Document

Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.


ATRX (α-Thalassemia/mental retardation syndrome X-linked) is a core component of a chromatin remodeling complex active in telomere biology. Mutations in ATRX gene have been identified in multiple tumor types and appear to cause alternative lengthening of telomeres (ALT).
Among some kind of gliomas, it is reported as IDH mutation, 1p/19q co-deletion and ATRX mutation are occurred and the detection of these marker is contribute to classify the type of the gliomas.
Anti ATRX, monoclonal antibody (AMab-6) is established against recombinant ATRX protein.


[Reactivity] Reacts with human ATRX
[Species cross reactivity] Human
[Clone No.] AMab-6
[Host] Mouse
[Isotype] IgG1·κ
[Concentration] Indicated on the label.
[Formulation] PBS (pH 7.4) containing sodium azide
[References]
1. Takano, S. et al., Brain Tumor Pathol., 33(2), 107-116 (2016).
2. Ogasawara, S., Fujii, Y., Kaneko, M. K., Oki, H., Sabit, H., Nakada, M., Suzuki, H., Ichimura, K., Komori, T. and Kato. Y., "Establishment of anti-Human ATRX monoclonal antibody AMab-6.", Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 35(5), 254-258 (2016).

Purpose Application:
[Western Blot] 1μg/mL ~
[Immunohistochemistry] 1 ~ 5μg/mL
[ELISA] 1μg/mL ~
Please optimize the most appropriate concentration for your analysis conditions and samples.

Property

Antibody Information

Antigen ATRX
Antigen Alias ATRX
EC 3.6.1.-
MGC2094
MRXS3
RAD54L
SHS
XH2
XNP
ZNF-HX
X-Linked Helicase II (ATRX)
alpha thalassemia/mental retardation syndrome X-linked
X-Linked Helicase II
Alpha Thalassemia/Mental Retardation Syndrome X-linked (RAD54 homolog) (ATRX)
ATRX / RAD54
ATR2, MGC2094, MRXS3, RAD54, RAD54L, SHS, XH2, XNP, ZNF-HX
alpha-thalassemia mental retardation X-linked
Rad54
RAD54 homolog, S. cerevisiae
ATR2
Subclass IgG1,k
Labeling Unlabeled

Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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