Cross-coupling reactions are an indispensable tool for organic synthesis. This method is significant and valuable for constructing C-C bond formation and is used in the field of industrial pharmaceutical, fine chemicals, functional electronic materials, etc. Heck reaction, Negishi coupling and Suzuki-Miyaura reactions were awarded the 2010 Nobel Prize in Chemistry for "developing Pd catalyzed cross coupling reactions". Several types of coupling reagents are available such as boronic acid, activating boronic compounds, cyclic triolborate, Ligand (SilicaSMAP), metal catalysts..

Author: D. Alwood


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