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Amyloid β Proteins, Peptides & Secretase inhibitors

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Amyloid β-Protein (Aβ) is known to accumulate in senile plaques found in the brains of patients with Alzheimer's disease. PEPTIDE Institute has a broad lineup including Amyloid β-Protein (Aβ) and L-685, 458, which are inhibitors of γ-secretase related to Alzheimer's disease.

References

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  2. J. Neurochem.,68, 438 (1997)
  3. Y. Sohma, M. Sasaki, Y. Hayashi, T. Kimura, and Y. Kiso, Tetrahedron Lett., 45, 5965 (2004); L.A. Carpino, E. Krause, C.D. Sferdean, M. Schuemann, H. Fabian, M. Bienert, and M. Beyermann, Tetrahedron Lett., 45, 7519 (2004).
  4. T. Yoshiya, T. Maruno, T. Uemura, S. Kubo, Y. Kiso, Y. Sohma, K. Yoshizawa-Kumagaye, Y. Kobayashi, and Y. Nishiuchi, Bioorg. Med. Chem. Lett., in press (2014) and references therein. DOI: 10.1016/j.bmcl.2014.06.052
  5. R. Roychaudhuri, A. Lomakin, S. Bernstein, X. Zheng, M.M. Condron, G.B. Benedek, M. Bowers, and D.B. Teplow, J. Mol. Biol., 426, 2422 (2014)
  6. Biochemistry., 39, 8698 (2000)
  7. Nature.,405, 689 (2000)
  8. J. Biol. Chem., 278, 24277 (2003)

Product List

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Amyloid β-Protein Fragments

Amyloid β-Protein Control Peptides

β-Secretase Inhibitor

β-Secretase Substrate

γ-Secretase Inhibitor

γ-Secretase Substrate

Antisera

Related Product List

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Amyloid β ELISA kit

Amyloid β antibody

Tau ELISA kit

Tau antibody

Tau protein

Other Alzheimer's disease related antibody

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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