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Ubiquinone-10

for Biochemistry
Specification Assay :
98.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
303-98-0
Molecular Formula :
C59H90O4
Molecular Weight :
863.34
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
216-00761
Barcode No
4987481347021
10mg
List Price
JPY 5,600

In stock in Japan

Distributor
212-00763
Barcode No
4987481347038
100mg
List Price
JPY 30,000

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline <Coenzyme>
CoQ10 is a coenzyme widely present in the living world as a liposoluble element of respiratory chain, and acts as an electron carrier in the electron transport system in mitochondria. As a pharmaceutical product, it is used for treatment and study of angina.
<Pharmacologic and Physiologic Research><Cardiovascular Active Substance>
The heart has automaticity due to the conducting system, and is also influenced by autonomic nerves. The sympathetic nerve acts in an exciting manner, and the parasympathetic nerve in a suppressive manner.
Physiological action of cardiotonic glycoside
It directly and selectively acts on the heart muscle and enhances the myocardial contractility.
- It acts on the process of excitation-contraction coupling, enhances the myocardial contractility, and increases the volume of blood pumped out. This effect occurs by inhibiting Na+, K+-ATPase of the cardiac sarcolemma and by inhibiting the Na+ pump.
- It decreases heart rate. This event is associated with the following two factors: 1. Factor via the vagal nerve (negative chronotropic effect ), and 2. Direct effect on the heart to delay conduction in the atrioventricular node (negative dromotropic action).
- The threshold value for stimuli from outside of the atrium and chamber increases by administration of digitalis, and sensitivity decreases. On the other hand, automaticity increases.
Therapeutic agent for antianginal effect, improvement of congestive heart failure, and treatment of cerebrovascular accident.

Property

Appearance Yellow - orange, crystalline powder - powder or mass
Melting Point 48 - 52 degrees C

Manufacturer Information

Alias

  • COENZYME Q10

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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