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Alendronate Sodium Salt Trihydrate

for Pharmacology Research
Specification Assay :
97.0+%(HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
121268-17-5
Molecular Formula :
C4H12NNaO7P2・3H2O
Molecular Weight :
325.12
GHS :
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
012-22661
Barcode No
4987481493070
100mg
List Price
JPY 15,000

In stock in Japan

Distributor
018-22663
Barcode No
4987481493087
500mg
List Price
JPY 67,800

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.

Osteoclastic Inhibitors: Research for Bone Metabolism

  • Alendronate Sodium Salt Trihydrate (Wako Cat. #012-22661; #018-22663)

  • Risedronate Sodium Salt n-Hydrate (Wako Cat. #189-02461; #185-02463)

Bone tissue is being remodeled by continuous deossification and ossification. The number of patients with osteoporosis caused by imbalance in the bone metabolism is increasing with the transition to an aging society.
This product is a bisphosphonate compound that is selectively distributed in the calcified bone surface to which the osteoclasts are attached. It is released under an acid environment created by the osteoclasts, taken in the cells, and inhibits the bone resorption activity. The inhibition of the bone resorption is considered to be caused by apoptosis induction effect of the osteoclasts and direct suppression of bone resorption of the osteoclasts.

Related Product:
TRAP/ALP Stain Kit (Wako Cat. #294-67001) - for enzyme activity staining of tartrate-resistant acid phosphatase -

Property

Appearance White - nearly white, crystals - powder
Melting Point about 252 degrees C (dec., After Drying)

Manufacturer Information

Alias

  • Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-, monosodium salt, trihydrate

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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