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Detail Information
  1. Top
  2. Cell Culture
  3. Animal Cell Culture
  4. Cytokine / Growth Factor
  5. Human, Recombinant Cytokines
  6. Fibroblast Growth Factor(basic) (FGF-basic / bFGF / FGF2), Human, recombinant(147aa)
  1. Top
  2. Cell Culture
  3. Stem Cell Culture
  4. Cytokine / Growth Factor
  5. Human, Recombinant Cytokines
  6. Fibroblast Growth Factor(basic) (FGF-basic / bFGF / FGF2), Human, recombinant(147aa)

Fibroblast Growth Factor(basic) (FGF-basic / bFGF / FGF2), Human, recombinant(147aa)

for Biochemistry
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
62031-54-3
Molecular Weight :
16.5kDa
Citations (3)
PubMed Central® search
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SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
067-04031
Barcode No
4987481387492
25ug
List Price
292.00 USD

In stock

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline FGF (fibroblast growth factor) family recently established to constitute a super family with IL-1 was found as a growth stimulating substance of fibroblastin, as its name shows, in the pituitary gland. Subsequently, two species with acidic and basic isoelectric points, respectively, have been elucidated and are called FGF-1=acidicFGF, and FGF-2=basicFGF. While it drew attention for a high affinity to heparin (another name is HBGF: heparin-binding growth factor) and a potent neovascularizing effect, it has been shown to accelerate growth of not only mesodermal cells such as myoblasts, vascular smooth muscle, chondrocytes, osteoblasts and glia, but also nerve cells and epithelial cells such as renal tubules, alveoli and thyroid gland. In neovascularization, it accelerates digestion of basal membrane and chemostaxis, proliferation and differentiation of vascular endothelial cells. Therefore, development as a therapeutic for wounds, and for myocardial infarction, central nervous disorder improving agent as well as therapeutic for tumor cells by inhibition of FGF has been advanced. In the past few years, there has emerged an an opinion that the angiogenic effect is based on induction of VEGF by FGF. This product consists of 147 amino acid residues in total with Met at the N-terminal. Molecular mass: 16.5 kDa

Property

Purity Bacterial endotoxins : <=0.1ng/ug

Manufacturer Information

Alias

  • basic FGF, human, rec
    rhbFGF
    HBGF-β

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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