microRNA (miRNA) are small functional RNA molecules (about 22 nucleotides) which act as posttranscriptional regulators of gene expression. They serve many functions within biological organisms, and more than 1,000 types are known to exist in humans and mice. Worldwide there are many efforts to identify new types of microRNA with unknown functions and elucidate functions of those involved in disease. Recently it has been reported that microRNA exist not only within cells, but also blood and other bodily fluids. They are now garnering attention as possible clinical markers for cancer and other diseases.
We offer a full selection of antibodies for various human and mouse Ago-subfamily proteins, as well as immunoprecipitation kits for them. These tools allow comprehensive analysis of microRNA and mRNA contained in RISC in cells and tissue, as well as Ago-bound microRNA in blood.