Nuclear Magnetic Resonance (NMR)
The NMR device is analytical instrument for the molecular structure of a substance at the atomic level by observing the nuclear spin resonance phenomenon by placing the chemicals in a strong magnetic field. Analysis of samples can be performed to the molecular structure at atomic level. It also has the advantage that pretreatment of the measurement sample is less than other analyzers. Conventionally, NMR has been used as a qualitative analysis, but due to the improvement in instrument performance, studies for quantitative analysis according to the number of moles are also underway.
In Japan, The use of qNMR techniques has matured to the point where Japanese Pharmacopoeia , Japan's Specifications and Standards for Food Additives and Japanese Industrial Standard (JIS) have adopted methodologies based on this technology. Identified as an efficient and faster approach pharmaceutical manufacturers are applying this technology for new drug development, quality management, process management and quality control.