Tetracaine Hydrochloride

for Biochemistry

Specification Assay :: 98.5+% (After Drying)(Titration)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at RT.

CAS RN^® :: 136-47-0
Molecular Formula :: C15H24N2O2HCl
Molecular Weight :: 300.82

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Comparison	Product Number	Package Size	Price	Inventory
	Distributor 207-09031 Barcode No 4987481340831	5G	Inquire	In stock in Japan	Certificate of Analysis
	Distributor 205-09032 Barcode No 4987481340848	25g		Discontinued	Certificate of Analysis

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Application

Overview / Applications

Outline	<Pharmacologic and Physiologic Research><Peripheral Nervous System Active Substance> Nerve cell membranes are charged negatively inside and positively outside in the static state with high extracellular concentrations of Na+ and Cl- and intracellular concentration of K+. However, upon excitation of cells, permeability of Na+ in the cell membrane is increased remarkably, and inflow of a large amount of Na+ into cells changes ion distribution generating action potential accompanying depolarization. The excited site where action potential is generated transmits impulses by exciting adjacent static regions in succession. Local anesthetics block excitation conduction in the sensory nerve (anesthetic effect) by lowering Na+ permeability in cell membranes and inhibiting depolarization (stabilization of membrane) necessary for excitation. The product blocks excitation conduction of the nerve by suppressing membrane permeability which accompanies the passage of impulses. Local anesthesia is achieved relatively fast and maintained for long periods of time. <Cellular Research><Calmodulin Inhibitor>

Outline

<Pharmacologic and Physiologic Research><Peripheral Nervous System Active Substance>
Nerve cell membranes are charged negatively inside and positively outside in the static state with high extracellular concentrations of Na+ and Cl- and intracellular concentration of K+. However, upon excitation of cells, permeability of Na+ in the cell membrane is increased remarkably, and inflow of a large amount of Na+ into cells changes ion distribution generating action potential accompanying depolarization. The excited site where action potential is generated transmits impulses by exciting adjacent static regions in succession. Local anesthetics block excitation conduction in the sensory nerve (anesthetic effect) by lowering Na+ permeability in cell membranes and inhibiting depolarization (stabilization of membrane) necessary for excitation.
The product blocks excitation conduction of the nerve by suppressing membrane permeability which accompanies the passage of impulses. Local anesthesia is achieved relatively fast and maintained for long periods of time.
<Cellular Research><Calmodulin Inhibitor>

Property

Appearance	White, crystals - crystalline powder
Melting Point	about 148 degrees C

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Product List

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For research use or further manufacturing use only. Not for use in diagnostic procedures.

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