PD0325901

for Cellbiology

Specification Assay :: 98.0+% (HPLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

CAS RN^® :: 391210-10-9
Molecular Formula :: C16H14F3IN2O4
Molecular Weight :: 482.19

Citations (17)

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Comparison	Product Number	Package Size	Price	Inventory
	Distributor 162-25291 Barcode No 4987481629837	5mg	Inquire	In stock in Japan	Certificate of Analysis
	Distributor 168-25293 Barcode No 4987481629844	25mg	Inquire	In stock in Japan	Certificate of Analysis

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Product Specification Sheet

Spectral Data

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5mg
25mg

Calibration Certificate

Overview / Applications

Outline	This product is for research use only. Do not administer it to human.PD0325901 is a MAPK inhibitor with potent antitumor activity. It induces phosphorylation of MAPK, inhibition of its activation and inhibition of tumor cell proliferation. PD0325901 inhibits MAPK activity without adverse reactions. Addition of this product and CHIR99021 to a culture medium results in efficient culture of mouse ES cells. It has been reported that use of this product with SB431542 and thiazovivin not only improves reprogramming efficiency 200 folds or more but also accelerates reprogramming speed.References: (1) Ying, Q. L. et al.: Nature, 453, 519 (2008)(2) Lin, T., et al.: Nat. Methods, 6, 805 (2009)

Outline

This product is for research use only. Do not administer it to human.PD0325901 is a MAPK inhibitor with potent antitumor activity. It induces phosphorylation of MAPK, inhibition of its activation and inhibition of tumor cell proliferation. PD0325901 inhibits MAPK activity without adverse reactions. Addition of this product and CHIR99021 to a culture medium results in efficient culture of mouse ES cells. It has been reported that use of this product with SB431542 and thiazovivin not only improves reprogramming efficiency 200 folds or more but also accelerates reprogramming speed.References: (1) Ying, Q. L. et al.: Nature, 453, 519 (2008)(2) Lin, T., et al.: Nat. Methods, 6, 805 (2009)

Property

Appearance	White - pale brown, crystals - powder

Manufacturer Information

Alias

N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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