Metoclopramide

for Biochemistry

Specification Assay :: 98.5+% (HPLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at RT.

CAS RN^® :: 364-62-5
Molecular Formula :: C14H22ClN3O2
Molecular Weight :: 299.80

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Comparison	Product Number	Package Size	Price	Inventory
	Distributor 138-10182 Barcode No 4987481296527	25G	Inquire	Inquire	Certificate of Analysis

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Application

Overview / Applications

Outline	A drug that inhibits excitation conduction from the sympathetic postganglionic fiber to target organs is referred to as a sympathetic nerve inhibitor or an antiadrenergic. Such drugs are classified into adrenergic receptor blocking agents and adrenergic nerve blocking agents according to the point of action.Adrenergic receptor blocking agent;It acts on the postsynaptic membrane and blocks sympathetic stimuli and the action of direct and indirect excitation substances. They are divided into alpha blockers (ergot alkaloids, imidazoline derivatives, haloalkylamine derivatives, etc.) and beta blockers (propranolol, sotalol, pindolol, etc.).Adrenergic nerve blocking agent;It acts on the anterosynaptic membrane and blocks sympathetic nerve stimuli and indirect excitation substances but does not affect the action of direct excitation substances working on receptors. They are divided into NE release inhibitors, NE exhaustion substances and NE synthesis inhibitors.NE release inhibitor: Blocks the association between nerve impulse and NE release. Bretylium, guanethidine, etc.NE exhaustion substance: Exhausts NE in storage granules. Reserpine, guanethidine, etc.NE synthesis inhibitor: Inhibits NE synthesis while forming false transmitters. Methyldopa, etc.Selective antagonist of dopamine D2 receptor. Controlling enterokinesis. Improves decreased gastric motility. Suppresses central and peripheral vomiting.

Outline

A drug that inhibits excitation conduction from the sympathetic postganglionic fiber to target organs is referred to as a sympathetic nerve inhibitor or an antiadrenergic. Such drugs are classified into adrenergic receptor blocking agents and adrenergic nerve blocking agents according to the point of action.Adrenergic receptor blocking agent;It acts on the postsynaptic membrane and blocks sympathetic stimuli and the action of direct and indirect excitation substances. They are divided into alpha blockers (ergot alkaloids, imidazoline derivatives, haloalkylamine derivatives, etc.) and beta blockers (propranolol, sotalol, pindolol, etc.).Adrenergic nerve blocking agent;It acts on the anterosynaptic membrane and blocks sympathetic nerve stimuli and indirect excitation substances but does not affect the action of direct excitation substances working on receptors. They are divided into NE release inhibitors, NE exhaustion substances and NE synthesis inhibitors.NE release inhibitor: Blocks the association between nerve impulse and NE release. Bretylium, guanethidine, etc.NE exhaustion substance: Exhausts NE in storage granules. Reserpine, guanethidine, etc.NE synthesis inhibitor: Inhibits NE synthesis while forming false transmitters. Methyldopa, etc.Selective antagonist of dopamine D2 receptor. Controlling enterokinesis. Improves decreased gastric motility. Suppresses central and peripheral vomiting.

Property

Appearance	White - nearly white, crystals - crystalline powder
Melting Point	146 - 149 degrees C

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Alias

Same CAS list

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