Anti Human Podocalyxin, Monoclonal Antibody (PcMab-47b)

for Immunochemistry

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

Source :: Human

Host :: Mouse
Clone No. :: PcMab-47b

Classification :: Monoclonal

Structural Formula
Label
Packing

SDS

Comparison	Product Number	Package Size	Price	Inventory
	Distributor 011-27491 Barcode No 4548995063885	100ug	Inquire	In stock in Japan	Certificate of Analysis

Inquiry

Document
Overview / Applications
Property
Antibody Information
Alias

Document

SDS ...all EN DE FR

Certificate of Analysis

100ug

Overview / Applications

Outline	Podocalyxin is a member of the CD34 family of type I transmembrane sialomucins. It is expressed in many normal cells such as renal podocytes and endothelial cells. It is also expressed in many types of tumors including colorectal cancers, breast cancers, and brain tumors. Overexpression of podocalyxin is an independent predictor of progression, metastasis, and poor prognosis. Recent studies indicate that the glycosylation of podocalyxin change depending on the state of the cells. Anti human podocalyxin, monoclonal antibody (PcMab-47b) is established against recombinant human podocalyxin. This antibody recognized endogenous podocalyxin expressing cancer cell lines and normal cells independently of glycosylation. [Reference] Ogasawara, S. et al., "PcMab-47: novel antihuman podocalyxin monoclonal antibody for immunohistochemistry.", Monoclon. Antib. Immunodiagn. Immunother., 36(2), 50-56 (2017).
Application	ELISA Flow Cytometry 1ug/mL~ Immunohistochemistry 1ug/mL~ *Please optimize the most appropriate concentration for your analysis conditions and samples.

Outline

Podocalyxin is a member of the CD34 family of type I transmembrane sialomucins. It is expressed in many normal cells such as renal podocytes and endothelial cells. It is also expressed in many types of tumors including colorectal cancers, breast cancers, and brain tumors. Overexpression of podocalyxin is an independent predictor of progression, metastasis, and poor prognosis. Recent studies indicate that the glycosylation of podocalyxin change depending on the state of the cells.
Anti human podocalyxin, monoclonal antibody (PcMab-47b) is established against recombinant human podocalyxin. This antibody recognized endogenous podocalyxin expressing cancer cell lines and normal cells independently of glycosylation.
[Reference]
Ogasawara, S. et al., "PcMab-47: novel antihuman podocalyxin monoclonal antibody for immunohistochemistry.", Monoclon. Antib. Immunodiagn. Immunother., 36(2), 50-56 (2017).

Application

ELISA
Flow Cytometry 1ug/mL~
Immunohistochemistry 1ug/mL~

*Please optimize the most appropriate concentration for your analysis conditions and samples.

Property

Composition	PBS containing sodium azide
Concentration	Protein : 1.0mg/mL (Absorptiometry)(280nm)

Antibody Information

Antigen	Podocalyxin
Antigen Alias	Podocalyxin PCX
Subclass	IgG1,k
Labeling	Unlabeled

Alias

PODXL Antibody

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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