Anti GFAP, Monoclonal Antibody(MO389)
- for Immunochemistry
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- Host :
- Mouse
- Clone No. :
- MO389
- Classification :
- Monoclonal
-
Close
Close
- Structural Formula
- Label
- Packing
|
Comparison
|
Product Number
|
Package Size
|
Price
|
Inventory
|
|
|---|---|---|---|---|---|
|
|
|
10uL
|
|
Discontinued
|
|
|
|
|
50uL
|
|
In stock in Japan |
Document
Product Overview
Glial fibrillary acidic protein (GFAP) is an intermediate filament protein with a molecular weight of approximately 50 kDa. GFAP is widely recognized as a marker for astrocytes, as it is primarily expressed in these cells within the central nervous system. It is thought to play a role in the structural organization of astrocytes. Previous studies have also shown that it is essential for the proliferation of reactive astrocytes and the formation of glial scars1-2). GFAP expression is known to increase under such pathological conditions compared to the normal state.
Anti GFAP, Monoclonal Antibody(MO389) is a mouse monoclonal antibody against GFAP. It is suitable for astrocyte staining in both immunohistochemistry and immunocytochemistry.
Antibody Information
| Clonality | Monoclonal |
|---|---|
| Antigen | Synthetic peptide (CQIRETpSLDTKS) |
| Host | Mouse |
| Formulation | PBS, 50% Glycerol |
| Conjugate | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Application | Immunocytochemistry 1:1,000 Immunohistochemistry 1:500 Western Blotting 1:10,000 |
Data
Application Data
Immunohistochemistry
Species: Mouse
Site: Thalamus
Sample: Frozen section
Antibody concentration: 1:500
Species: Mouse
Site: Hippocampus
Sample: Frozen section
Antibody concentration: 1:500
Immunocytochemistry
Cell line: U251 (Human astrocytoma)
Antibody concentration: 1:1,000
References
- Sofroniew, M. V. and Vinters, H. V.: Acta Neuropathol., 119, 7(2010).
Astrocytes: biology and pathology - Pekny, M. and Pekna, M.: J. Pathol., 204(4), 428(2004).
Astrocyte intermediate filaments in CNS pathologies and regeneration
FAQ
About application
- What animals can this antibody be used for?
- Fujifilm Wako has confirmed that it can be used for humans and mice. Other species have not been tested.
Property
Antibody Information
| Antigen | GFAP |
|---|---|
| Antigen Alias | GFAP Glial Fibrillary Acidic Protein GFAP Cocktail FLJ45472 GFAP - glial fibrillary acidic protein Glial Fibrillary Acidic Protein (GFAP) |
| Subclass | IgG1 |
| Labeling | Unlabeled |
Manufacturer Information
Alias
- Anti Glial Fibrillary Acid Protein, Monoclonal Antibody(MO389)
For research use or further manufacturing use only. Not for use in diagnostic procedures.
Product content may differ from the actual image due to minor specification changes etc.
If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.