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PD0325901

for Cellbiology
Specification Assay :
98.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
391210-10-9
Molecular Formula :
C16H14F3IN2O4
Molecular Weight :
482.19
GHS :
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
162-25291
Barcode No
4987481629837
5mg
List Price
JPY 19,800

In stock in Japan

Distributor
168-25293
Barcode No
4987481629844
25mg
List Price
JPY 74,800

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.PD0325901 is a MAPK inhibitor with potent antitumor activity. It induces phosphorylation of MAPK, inhibition of its activation and inhibition of tumor cell proliferation. PD0325901 inhibits MAPK activity without adverse reactions. Addition of this product and CHIR99021 to a culture medium results in efficient culture of mouse ES cells. It has been reported that use of this product with SB431542 and thiazovivin not only improves reprogramming efficiency 200 folds or more but also accelerates reprogramming speed.References: (1) Ying, Q. L. et al.: Nature, 453, 519 (2008)(2) Lin, T., et al.: Nat. Methods, 6, 805 (2009)

Property

Appearance White - pale brown, crystals - powder

Manufacturer Information

Alias

  • N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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