Piceatannol

for Cellbiology

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at 2-10 degrees C.

CAS RN^® :: 10083-24-6
Molecular Formula :: C14H12O4
Molecular Weight :: 244.24

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Comparison	Product Number	Package Size	Price	Inventory
	Distributor 169-21661 Barcode No 4987481442115	10mg	List Price JPY 23,100	Inquire	Certificate of Analysis

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Overview / Applications

Outline	An activator of human deacetylase class III (SIRT1).An inhibitor of non-reception type tyrosine kinase Syk. This product is for research use only. Do not administer it to human. Cell Biological ResearchFor Research on Cell Cycle and TranscriptionHistone deacetylase (HDAC) plays a central role in chromatin structure formation associated with the nuclear distribution of DNA. There are presently 17 known types of this enzyme in mammals, which are classified into 3 classes (see below). Also, HDAC Class III has been reported to be associated with regulation of aging and life span. Mammalian HDAC Class I: Localized in the nucleus. Is similar to RPD3 enzyme. [Types: HDAC1-3, 8] Mammalian HDAC Class II: Localized in the nucleus and cytoplasm and shuttles between the two. Similar to HDAC1 enzyme. [Types: HDAC4-7, 9, 10] Mammalian HDAC Class III: NAD-dependent enzyme. Localized in the nucleus and cytoplasm. Also called Sirtuin and is similar to SIR2 enzyme. [Types: Sirt 1-7] [Related Products] Piceatannol (Wako Cat.#169-21661 (10 mg)) Activator of HDAC Class III and inhibitor of kinase Syk. Sirtinol (Wako Cat.#197-13671 (5 mg)) Inhibitor of HDAC Class III. Cell-permeable. Trichostatin A (Wako Cat.#203-17561 (1 mg); #209-17563 (5 mg)) Potent and reversible inhibitor of HDAC Class I and II. Valproic Acid (Wako Cat.#227-01071 (5 g); #225-01072 (25 g)) Inhibitor of HDAC1. [Reference]1) Howitz, K. T., et al.: Nature, 425, 191 (2003). Shown on the page #4 of Wako Product Update No. 13.

Outline

An activator of human deacetylase class III (SIRT1).An inhibitor of non-reception type tyrosine kinase Syk.
This product is for research use only. Do not administer it to human.

Cell Biological ResearchFor Research on Cell Cycle and TranscriptionHistone deacetylase (HDAC) plays a central role in chromatin structure formation associated with the nuclear distribution of DNA. There are presently 17 known types of this enzyme in mammals, which are classified into 3 classes (see below). Also, HDAC Class III has been reported to be associated with regulation of aging and life span.

Mammalian HDAC Class I: Localized in the nucleus. Is similar to RPD3 enzyme. [Types: HDAC1-3, 8]
Mammalian HDAC Class II: Localized in the nucleus and cytoplasm and shuttles between the two. Similar to HDAC1 enzyme. [Types: HDAC4-7, 9, 10]
Mammalian HDAC Class III: NAD-dependent enzyme. Localized in the nucleus and cytoplasm. Also called Sirtuin and is similar to SIR2 enzyme. [Types: Sirt 1-7]

[Related Products]
Piceatannol (Wako Cat.#169-21661 (10 mg))
Activator of HDAC Class III and inhibitor of kinase Syk.

Sirtinol (Wako Cat.#197-13671 (5 mg)) Inhibitor of HDAC Class III. Cell-permeable.

Trichostatin A (Wako Cat.#203-17561 (1 mg); #209-17563 (5 mg)) Potent and reversible inhibitor of HDAC Class I and II.

Valproic Acid (Wako Cat.#227-01071 (5 g); #225-01072 (25 g)) Inhibitor of HDAC1.

[Reference]1) Howitz, K. T., et al.: Nature, 425, 191 (2003).
Shown on the page #4 of Wako Product Update No. 13.

Property

Appearance	White - brown, crystals - powder

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Alias

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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