Prostaglandin I2 Sodium Salt

for Biochemistry

Specification Assay :: 98+% (TLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

CAS RN^® :: 61849-14-7
Molecular Formula :: C20H31NaO5
Molecular Weight :: 374.45

GHS :

Structural Formula
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Comparison	Product Number	Package Size	Price	Inventory
	Distributor 169-14331 Barcode No 4987481317550	1mg	List Price JPY 25,400	In stock in Japan	Certificate of Analysis

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Overview / Applications

Outline	Autacoids are biologically active substances that, like hormones, exhibit strong bioactivity at extremely low concentrations, but unlike hormones exhibit the strong bioactivity not in a particular producing organ but at the site where it is produced. In chemical terms, autacoids are classified into amines (such as histamine and serotonin), peptides (such as bradykinin and angiotensin) and fatty acids (such as prostaglandin). Prostaglandins have a complex biosynthesis pathway, and the unsaturated fatty acid arachidonic acid is a precursor that is present in the largest quantity. Prostaglandins are distributed throughout the body including the prostate. Inhibitors of prostaglandin biosynthesis include non-steroidal antiinflammatory drugs such as indomethacin, phenylbutazone and aspirin, and inhibition of prostaglandin biosynthesis is attracting attention as one of the antiinflammatory mechanisms of these drugs. The Prostaglandin E series increases the sensitivity of pain sensation acceptors for algesic substances such as bradykinin. Hypotensive, platelet agglutination inhibitory, cAMP increasing, gastric secretion inhibitory and Na+ excretion enhancing actions.

Outline

Autacoids are biologically active substances that, like hormones, exhibit strong bioactivity at extremely low concentrations, but unlike hormones exhibit the strong bioactivity not in a particular producing organ but at the site where it is produced. In chemical terms, autacoids are classified into amines (such as histamine and serotonin), peptides (such as bradykinin and angiotensin) and fatty acids (such as prostaglandin).

Prostaglandins have a complex biosynthesis pathway, and the unsaturated fatty acid arachidonic acid is a precursor that is present in the largest quantity.
Prostaglandins are distributed throughout the body including the prostate.
Inhibitors of prostaglandin biosynthesis include non-steroidal antiinflammatory drugs such as indomethacin, phenylbutazone and aspirin, and inhibition of prostaglandin biosynthesis is attracting attention as one of the antiinflammatory mechanisms of these drugs.
The Prostaglandin E series increases the sensitivity of pain sensation acceptors for algesic substances such as bradykinin.
Hypotensive, platelet agglutination inhibitory, cAMP increasing, gastric secretion inhibitory and Na+ excretion enhancing actions.

Property

Appearance	White - pale yellow, crystalline powder - powder

Manufacturer Information

Alias

PROSTAGLANDIN I2.NA

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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