Aprotinin, from Bovine Lung

for Biochemistry

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at 2-10 degrees C.

CAS RN^® :: 9087-70-1
Molecular Weight :: 6,511.53

GHS :

Citations (3)

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SDS

Product Number	Package Size	Price	Inventory
Distributor 010-11834 Barcode No 4987481374614	50000KIU	List Price JPY 12,100	In stock in Japan	Certificate of Analysis
Distributor 012-11833 Barcode No 4987481209145	100000KIU	List Price JPY 20,000	In stock in Japan	Certificate of Analysis
Distributor 014-11832 Barcode No 4987481382596	200000KIU	List Price JPY 33,900	In stock in Japan	Certificate of Analysis
Distributor 016-11836 Barcode No 4987481382602	750000KIU	List Price JPY 119,200	In stock in Japan	Certificate of Analysis

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Spectral Data

Certificate of Analysis

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Overview / Applications

Outline	A protease inhibitor which inhibits trypsin, plasmin, plasma kallikrein, and tissue kallikrein.It is a polypeptide with a molecular weight of 6512 which consists of 58 amino acids and is used as inhibitor of blood coagulation and fibrinolysis. The molecule has three S-S bonds, and belongs to the group of Kunltz-type protease inhibitors. It hardly inhibits thrombin, while it shows marked inhibitory action on plasma and tissue kallikreins so that it is used in studies on protease inhibitors and blood coagulation system.Amino acid sequence:H-Arg-Pro-Asp-Phe-Cys-Leu-Glu-Pro-Pro-Tyr-Thr-Gly-Pro-Cys-Lys-Ala-Arg-Ile-Ile-Arg-Tyr-Phe-Tyr-Asn-Ala-Lys-Ala-Gly-Leu-Cys-Gln-Thr-Phe-Val-Tyr-Gly-Gly-Cys-Arg-Ala-Lys-Arg-Asn-Asn-Phe-Lys-Ser-Ala-Glu-Asp-Cys-Met-Arg-Thr-Cys-Gly-Gly-Ala-OH(disulfide bonds: 5->55, 14->38, 30->51).KIE unit: "KIE" is German abbreviation for KIU in English. (Einheit=Unit)FIP-unit: 1 FIP is defined as the amount of trypsin which hydrolyses 1 micromole of the substrate (BAEE) under the conditions of the FIP method at pH 8 and 25 degrees C.Inhibition of trypsin activity of 32.5 FIP is defined as 1KIU.1 TIU (Trypsin Inhibitor Unit) ≈ 900 KIU)8 UIP (Peptidases Inhibitor Units) = 1 KIU

Outline

A protease inhibitor which inhibits trypsin, plasmin, plasma kallikrein, and tissue kallikrein.It is a polypeptide with a molecular weight of 6512 which consists of 58 amino acids and is used as inhibitor of blood coagulation and fibrinolysis. The molecule has three S-S bonds, and belongs to the group of Kunltz-type protease inhibitors. It hardly inhibits thrombin, while it shows marked inhibitory action on plasma and tissue kallikreins so that it is used in studies on protease inhibitors and blood coagulation system.Amino acid sequence:H-Arg-Pro-Asp-Phe-Cys-Leu-Glu-Pro-Pro-Tyr-Thr-Gly-Pro-Cys-Lys-Ala-Arg-Ile-Ile-Arg-Tyr-Phe-Tyr-Asn-Ala-Lys-Ala-Gly-Leu-Cys-Gln-Thr-Phe-Val-Tyr-Gly-Gly-Cys-Arg-Ala-Lys-Arg-Asn-Asn-Phe-Lys-Ser-Ala-Glu-Asp-Cys-Met-Arg-Thr-Cys-Gly-Gly-Ala-OH(disulfide bonds: 5->55, 14->38, 30->51).KIE unit: "KIE" is German abbreviation for KIU in English. (Einheit=Unit)FIP-unit: 1 FIP is defined as the amount of trypsin which hydrolyses 1 micromole of the substrate (BAEE) under the conditions of the FIP method at pH 8 and 25 degrees C.Inhibition of trypsin activity of 32.5 FIP is defined as 1KIU.1 TIU (Trypsin Inhibitor Unit) ≈ 900 KIU)8 UIP (Peptidases Inhibitor Units) = 1 KIU

Property

Appearance	White - slightly yellow, crystals - powder
Activity	min. 6000KIU/mg

Manufacturer Information

Alias

APROTININ, BOVINE LUNG

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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